Facklamia hominis

Facklamia hominis Overview

Facklamia hominis is a rarely reported gram-positive coccus occasionally isolated from urine; only a few cases of F. hominis urinary infections (including pyelonephritis) have been documented. Because F. hominis resembles viridans streptococci and can be misidentified, it is likely underrecognized, and one report suggests it may be a facultative pathogen whose incidence could rise with better detection. Including F. hominis on the panel helps identify these rare UTI cases that would otherwise be missed (Pérez-Cavazos et al.  2022, Moreland et al. 2023).

Reference:

Pérez-Cavazos, S., Cisneros-Saldaña, D., Espinosa-Villaseñor, F., Castillo-Bejarano, J. I., Vaquera-Aparicio, D. N., Sánchez-Alanís, H., & Mascareñas-De Los Santos, A. (2022). Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literatureAnnals of clinical microbiology and antimicrobials21(1), 4. https://doi.org/10.1186/s12941-022-00497-4

Moreland RB, Choi BI, Geaman W, Gonzalez C, Hochstedler-Kramer BR, John J, Kaindl J, Kesav N, Lamichhane J, Lucio L, Saxena M, Sharma A, Tinawi L, Vanek ME, Putonti C, Brubaker L, Wolfe AJ. 2023. Beyond the usual suspects: emerging uropathogens in the microbiome age. Front Urol 3:1212590

Products used to detect Facklamia hominis

The emerging UTI PCR panel 2 is designed for multiplex in vitro assessment of four emerging uropathogens (A. urinae, F. hominis, S. anginosis group, and W. neuii), using real-time PCR.