Human Metapneumovirus (HMPV)

Human Metapneumovirus (HMPV) Overview

HMPV is a paramyxovirus discovered in 2001 that causes seasonal respiratory infections (bronchiolitis, pneumonia) similar in severity to RSV, especially in young children and the elderly. It is clinically relevant to include because HMPV accounts for a significant fraction of pediatric hospitalizations (on the order of 5–10% annually) and can cause outbreaks of severe lower respiratory disease Charlton et al.  2018, Panda et al.  2014).

References:

Charlton, C. L., Babady, E., Ginocchio, C. C., Hatchette, T. F., Jerris, R. C., Li, Y., Loeffelholz, M., McCarter, Y. S., Miller, M. B., Novak-Weekley, S., Schuetz, A. N., Tang, Y. W., Widen, R., & Drews, S. J. (2018). Practical Guidance for Clinical Microbiology Laboratories: Viruses Causing Acute Respiratory Tract InfectionsClinical microbiology reviews32(1), e00042-18. https://doi.org/10.1128/CMR.00042-18

Panda, S., Mohakud, N. K., Pena, L., & Kumar, S. (2014). Human metapneumovirus: review of an important respiratory pathogenInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases25, 45–52. https://doi.org/10.1016/j.ijid.2014.03.1394

Products used to detect Human Metapneumovirus (HMPV)

The x-large respiratory PCR panel is designed for multiplex in vitro assessment of 25 common respiratory microbiota and resistance markers, using real-time PCR.