Mycoplasma hominis is a fastidious bacterium lacking a cell wall, which can colonize the genitourinary tract and occasionally cause UTIs, especially in immunosuppressed or pregnant individuals. Because it cannot be detected using standard culture methods and is intrinsically resistant to β-lactam antibiotics, molecular detection via PCR is crucial. Its involvement in persistent, atypical urinary symptoms makes it a relevant diagnostic target (Valentine-King & Brown 2017, Abankwa et al. 2024)
Valentine-King MA, Brown MB. Antibacterial Resistance in Ureaplasma Species and Mycoplasma hominis Isolates from Urine Cultures in College-Aged Females. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e01104-17. doi: 10.1128/AAC.01104-17. PMID: 28827422; PMCID: PMC5610494.
Abankwa A, Sansone S, Aligbe O, Hickner A, Segal S. The Role of Ureaplasma and Mycoplasma Species in Recurrent Lower Urinary Tract Infection in Females: A Scoping Review. Reprod Sci. 2024 Jul;31(7):1771-1780. doi: 10.1007/s43032-024-01513-y. Epub 2024 Mar 20. PMID: 38509400.
