The Streptococcus anginosus group (SAG) – comprising S. anginosus, S. constellatus, and S. intermedius – are part of the genitourinary flora and can cause serious pyogenic infections. Although they are not classic uropathogens, SAG species can cause invasive, abscess-forming UTIs (often polymicrobial) that are missed by standard culture. Including SAG in a PCR panel ensures detection of these underrecognized pathogens in complicated UTIs (Jiang et al. 2020, Pilarczyk-Zurek et al. 2022).
Jiang, S., Li, M., Fu, T., Shan, F., Jiang, L., & Shao, Z. (2020). Clinical Characteristics of Infections Caused by Streptococcus Anginosus Group. Scientific reports, 10(1), 9032. https://doi.org/10.1038/s41598-020-65977-z
Pilarczyk-Zurek M, Sitkiewicz I, Koziel J. The Clinical View on Streptococcus anginosus Group – Opportunistic Pathogens Coming Out of Hiding. Front Microbiol. 2022 Jul 8;13:956677.
