BlazedX Oncology Mutation Panels

Fast, Sensitive, and Economical Mutation Detection

Cancer mutation profiling is essential for guiding decisions—but NGS-based methods are expensive and slow for routine use. BlazedX Oncology Panels bring high-value mutation detection to laboratories with fast, cost-effective qPCR-based assays built around patented Switch-Blocker™ technology. Get answers in under 4 hours. 

EGFR workflow timeline comparison Comparison between an NGS workflow taking two to four weeks and Tsunami plus Trio taking under three hours. NGS WORKFLOW 2-4 WEEKS FFPE extract Library prep Sequencing run Bioinformatics Report TSUNAMI + TRIO UNDER 3 HOURS FFPE prep on Trio→qPCR→analysis→report

Streamlined qPCR Workflow

BlazedX Oncology Panels are designed to detect actionable somatic mutations in key driver genes across multiple tumor types. Using a simple qPCR workflow on standard 5-channel instruments, our panels provide rapid mutation presence/absence screening with the option to reflex to  confirmatory NGS.

Tsunami EGFR Panel

BlazedX Tsunami EGFR Panel screens 13 actionable EGFR targets, across 5 wells. Includes RNAse P probe for sample adequacy and redundant probes for deletions.

Exon 19 Deletions: T790M C797S Codon 858 Substitutions:
In-frame deletions, exon 19 Acquired resistance to 1st/2nd gen TKI’s. Resistance to 3rd gen TKI’ Activating substitutions
p. L474_T175del T790M C797 T>A L858R
p. E746_A750del C797S G>C L858M
p. L747_P753delinsS L858Q

Specifications:

Sample input: Up to 50 ng FFPE-extracted gDNA
Reactions: 48 test samples per kit
Plate format: 96-well, 0.2 mL
Reaction size: 10 µl, 5 wells
Instruments: QuantStudio™ 5, 7, Flex
Cycling time: 1 hour, 25 minutes
End-to-end: Under 4 hours with Trio
Storage: −20°C
Software: QuantStudio Design & Analysis (.edt) file supplied

Why Choose BlazedX Oncology Panels?

  • qPCR Simplicity - Run assays on standard 5-channel platforms—no sequencing or proprietary systems required.
  • Fast Results - Mutation screening in under 4 hours with Trio extraction device for FFPE
  • Economical and Scalable - Lower per-sample cost than NGS and optimized for flexible throughput.
  • High Sensitivity - Detects mutations with minor allele frequency (MAF) > 0.1%—10× more sensitive than typical NGS thresholds.
  • Made for Real-World Samples - Compatible with FFPE, plasma, urine, whole blood, and solid tumor DNA.

Gene Mutation Prevalence by Disease

Ideal for Research in:

  • Oncology

Made in the USA. Research Use Only.

Empowering Your Lab

BlazedX Oncology Panels enable fast, reliable frontline mutation testing—without the cost, complexity or delay of sequencing. Our qPCR-based assays help you deliver answers with speed, confidence, and control.

Made in the USA. Research Use Only.

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